Table 2. Anthropometric characteristics, oxidative damage biomarkers, and antioxidant defense of the study groups.
| Variables | NW (n = 15) | CIIO (n = 15) | P-value | |
|---|---|---|---|---|
| Weight (kg) | 68.1 ± 2.2 | 104.8 ± 6.14* | 0.0001 | |
| Age (yrs) | 22.1 ± 0.2 | 22.1 ± 0.33 | 0.4533 | |
| Height (m) | 1.7 ± 0.01 | 1.7 ± 0.01 | 0.7533 | |
| BMI (kg/m2) | 23.3 ± 0.6 | 35.7 ± 1.8* | 0.0001 | |
| DBP | 82.6 ± 5.97 | 82.6 ± 2.06 | 0.4438 | |
| SBP | 109.3 ± 2.84 | 120 ± 2.4 | 0.0682 | |
| Biomarkers of oxidative damage | ||||
| MDA (µM) | 2.21 ± 0.27 | 3.13 ± 0.28* | 0.0265 | |
| 4-HNE (µM) | 2.33 ± 0.30* | 1.34 ± 0.11 | 0.0065 | |
| Carbonyl groups (nmol/mg protein) | 0.64 ± 0.02 | 0.51 ± 0.01 | 0.3920 | |
| Biomarkers of defense antioxidant | ||||
| TAC (µM) | 0.75 ± 0.02 | 0.58 ± 0.01* | 0.0001 | |
| Thiol groups (nmol/mg protein) | 3.32 ± 0.47 | 3.37 ± 0.77 | 0.9375 | |
Data are shown as mean ± SE and intergroup differences were analyzed by Student’s t-test *P < 0.05.
NW, normoweight; CIIO, class II obesity; BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure, MDA, malondialdehyde; 4-HNE, 4-hydroxynonenal; TAC: total antioxidant capacity.