Table 1.
At least one dispensing of aspirin | Total | ||||||
---|---|---|---|---|---|---|---|
No | Yes | p-value | |||||
(N=16,068) | (N=12,399) | (N=28,467) | |||||
N | % | N | % | N | % | ||
Characteristics at the beginning of the 2nd pregnancy | |||||||
Mean age (SD) (years) | 30.0 | 5.0 | 31.0 | 4.7 | <0.0001 | 30.5 | 4.9 |
Social deprivation | 3338 | 20.8 | 1693 | 13.7 | <0.0001 | 5031 | 17.7 |
Obesity | 1935 | 12.0 | 1392 | 11.2 | 0.0336 | 3327 | 11.7 |
Diabetes | 265 | 1.7 | 231 | 1.9 | 0.1716 | 496 | 1.7 |
Tobacco use | 1328 | 8.3 | 1067 | 8.6 | 0.3046 | 2395 | 8.4 |
Chronic hypertension | 2396 | 14.9 | 2938 | 23.7 | <0.0001 | 5334 | 18.7 |
Characteristics of the 1st pregnancy | |||||||
Multiple pregnancy | 621 | 3.9 | 295 | 2.4 | <0.0001 | 916 | 3.2 |
Caesarean section | 7594 | 47.3 | 8821 | 71.1 | <0.0001 | 16415 | 57.7 |
Preterm birth (< 37 WG) | 3619 | 22.5 | 7711 | 62.2 | <0.0001 | 11330 | 39.8 |
IUFD | 14 | 0.1 | 34 | 0.3 | 0.0001 | 48 | 0.2 |
Gestational diabetes | 1725 | 10.7 | 1101 | 8.9 | <0.0001 | 2826 | 9.9 |
Obstetrical haemorrhage | 1407 | 8.8 | 1052 | 8.5 | 0.4180 | 2459 | 8.6 |
PE subtypes (1st pregnancy) | <0.0001 | ||||||
Mild and late PE | 11295 | 70.3 | 4341 | 35.0 | 15636 | 54.9 | |
Severe and late PE | 3522 | 21.9 | 4161 | 33.6 | 7683 | 27.0 | |
Mild and early | 484 | 3.0 | 857 | 6.9 | 1341 | 4.7 | |
Severe and early PE | 767 | 4.8 | 3040 | 24.5 | 3807 | 13.4 |
IUFD intra-uterine foetal death, PE pre-eclampsia, SD standard deviation, WG weeks of gestation