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. 2023 Mar 3;83(5):429–437. doi: 10.1007/s40265-023-01842-3

Table 1.

Characteristics according to prescribed dispensing of aspirin

At least one dispensing of aspirin Total
No Yes p-value
(N=16,068) (N=12,399) (N=28,467)
N % N % N %
Characteristics at the beginning of the 2nd pregnancy
Mean age (SD) (years) 30.0 5.0 31.0 4.7 <0.0001 30.5 4.9
Social deprivation 3338 20.8 1693 13.7 <0.0001 5031 17.7
Obesity 1935 12.0 1392 11.2 0.0336 3327 11.7
Diabetes 265 1.7 231 1.9 0.1716 496 1.7
Tobacco use 1328 8.3 1067 8.6 0.3046 2395 8.4
Chronic hypertension 2396 14.9 2938 23.7 <0.0001 5334 18.7
Characteristics of the 1st pregnancy
Multiple pregnancy 621 3.9 295 2.4 <0.0001 916 3.2
Caesarean section 7594 47.3 8821 71.1 <0.0001 16415 57.7
Preterm birth (< 37 WG) 3619 22.5 7711 62.2 <0.0001 11330 39.8
IUFD 14 0.1 34 0.3 0.0001 48 0.2
Gestational diabetes 1725 10.7 1101 8.9 <0.0001 2826 9.9
Obstetrical haemorrhage 1407 8.8 1052 8.5 0.4180 2459 8.6
PE subtypes (1st pregnancy) <0.0001
Mild and late PE 11295 70.3 4341 35.0 15636 54.9
Severe and late PE 3522 21.9 4161 33.6 7683 27.0
Mild and early 484 3.0 857 6.9 1341 4.7
Severe and early PE 767 4.8 3040 24.5 3807 13.4

IUFD intra-uterine foetal death, PE pre-eclampsia, SD standard deviation, WG weeks of gestation