Table 1.
Preoperative characteristics of patients with perforated peptic ulcers treated with various surgical approaches
| Overall n = 175 | Laparoscopy group n = 77 | Converted to open group n = 27 | Open group n = 71 | p value LG vs. CG | p value CG vs. OG | p value LG vs. OG | |
|---|---|---|---|---|---|---|---|
| Male gender, n (%) | 96 (54.8) | 48 (62.3) | 16 (59.2) | 32 (45) | 0.95 | 0.30 | 0.05 |
| Age, years, mean (± SD) | 64.5 (± 19.7) | 55.9 (± 19.4) | 65.5 (± 14.1) | 73.5 (± 17.49) | 0.05 | 0.01 | < 0.0001 |
| BMI, kg/m2, mean (± SD) | 24.2 (± 4.3) | 23.9 (± 3.2) | 25.3 (± 4.6) | 24.7 (± 4.9) | 0.12 | 0.50 | 0.24 |
| Co-morbidities, n (%) | 120 (68.6) | 40 (51.9) | 20 (74) | 60 (84.5) | 0.26 | 0.36 | < 0.0001 |
| Pre-existing PPI treatment, n (%) | 23 (13.1) | 8 (10.3) | 2 (7.4) | 13 (18.3) | 0.20 | 0.22 | 0.25 |
| Smoking status, n (%) | 74 (42.2) | 32 (41.5) | 15 (55.5) | 27 (38) | 0.62 | 0.18 | 0.78 |
| Previous abdominal surgery, n (%) | 46 (26.2) | 9 (11.6) | 8 (29.6) | 29 (40.8) | 0.02 | 0.43 | 0.0001 |
| Charlson comorbidity index, mean (± SD) | 3.1 (2.4) | 1.9 (2.1) | 3 (1.7) | 4.8 (2.1) | 0.03 | 0.02 | < 0.0001 |
| Time presentation/treatment (hs) mean (± SD) | 31.7 (23.8) | 30.9 (24.4) | 28.4 (21.9) | 33.8 (23.9) | 0.66 | 0.26 | 0.34 |
| Boey score mean (± SD) | 1.2 (0.8) | 0.8 (0.6) | 1.4 (0.7) | 1.6 (0.8) | 0.003 | 0.25 | < 0.0001 |
| ASA score, median (IQR) | 3 (1–4) | 2 (2–3) | 2 (1.9–2.3) | 3 (3.1–3.4) | 0.29 | 0.23 | 0.06 |
| Mannheim peritonitis index, mean (± SD) | 20.6 (± 6.2) | 19.1 (5.2) | 21.8 (6.4) | 21.6 (6.9) | 0.04 | 0.89 | 0.05 |
Bolding indicates statistically significant differences (p < 0.05)
ASA American Society of Anesthesiology score BMI Body Mass Index, PPI Proton Pump Inhibitor, SD Standard Deviation, IQR Interquartile Range, y years