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. 2022 Oct 7;44(4):877–887. doi: 10.1038/s41401-022-00999-z

Fig. 3. The validation of the four active compounds at cellular and molecular level.

Fig. 3

Dose-response curves of cell viability in HEK293T, SK-N-AS, IMR32, and LAN5 cell lines after 72-h treatment and SPR sensorgrams of the compounds 11 (a), 13 (b), 19 (c) and 22 (d) tested by CCK-8 assay and Biacore 8 K, respectively.