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. 2023 Mar 14;10:1116722. doi: 10.3389/fvets.2023.1116722

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Copyright © 2023 Canelli, Ferrari, Borghetti, Candela, Abiakam, Bianchera, Buttini, Magi, Sonvico, Martelli and Bettini.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histological features of nasal mucosa sections in the IN-vaccinated (nano-adjuvanted dry powder vaccine) group at 7 days PV. (A) Immune cell infiltrate within lamina propria mainly composed of lymphocytes (yellow circle), plasma cells (blue arrow) and macrophages (green arrow) with rare eosinophils (yellow arrow) (630× magnification); (B) numerous intraepithelial lymphocytes within epithelium (green arrow) (400× magnification). IN, intranasally.