Table 2.
Echocardiographic predictors of all-cause mortality in patients with aortic stenosis and ATTRwt-CA.
| Study | Cavalcante et al. (5) | Rosenblum et al. (7) | Treibel et al. (9) | Rubin et al. (29) |
|---|---|---|---|---|
| Mitral annular S′ (cm/s) | Not a predictor of all-cause mortality HR 0.77 (0.56–1.06, 95% CI, p .10) |
Not a predictor of all-cause mortality HR 0.89 (0.77–1.04, 95% CI, p .150) |
NA | NA |
| IVST (cm) | Not a predictor of all-cause mortality HR 3.14 (1.03–9.56, 95% CI, p .04) |
Not a predictor of all-cause mortality HR 1.56 (0.94–2.57, 95% CI, p .083) |
NA | NA |
| AV mean gradient (mmHg) | Not a predictor of all-cause mortality HR 0.98 (0.96-1.00 95% CI p .13) |
NA | Not a predictor of all-cause mortality HR 0.96 (0.92–1.00 95% CI p .07) | NA |
| E/e′ ratio | Predictor of all-cause mortality HR 1.02 (1.006, 1.04 95% CI p .01) |
NA | NA | NA |
| LV mass index (g/m2) | NA | NA | Predictor of all-cause mortality HR 1.03 (1.00–1.52 95% CI p .05) |
NA |
| SVi (mL/m2) | Predictor of all-cause mortality HR 0.95 (0.92, 0.98 95% CI p .001) |
Predictor of all-cause mortality HR 1.67 (1.00–2.79 95%CI p .049) |
NA | NA |
| LAVi (mL/m2) | Predictor of all-cause mortality HR 1.04 (1.02, 1.06 95% CI p < .001) |
NA | NA | NA |
| GLS | NA | NA | NA | NA |
| MCF (%) | NA | Predictor of all-cause mortality HR 0.98 (0.96–1.00 95% CI p .041) |
NA | Predictor of all-cause mortality HR 5.4 (1.82–15.86, 95% CI p .0024) |
AV, aortic valve; GLS, global longitudinal strain; IVST, interventricular septal thickness; LV, left ventricular; Svi, left ventricular stroke volume index; MCF, myocardial contraction fraction; DT, deceleration time; LAVi, left atrial volume index; NA, not available.