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. 2023 Mar 14;10:1130623. doi: 10.3389/fmed.2023.1130623

Table 1.

Characteristics of included studies.

Author Year Site Age (Mean ± SD) Number Severity Causes of hair loss Duration Frequence (daily) Dose Change in length or density Mode of assessment Side effects (n)
Gurpreet S. Ahluwalia et al. 2013 eyelash NA Bimatoprost:96
Placebo:34
severe chemotherapy 12 m 1 0.05 mL Placebo:35.6 digital image analysis Bimatoprost:12
Placebo:0
Bimatoprost:39.1
A. Rossi et al. 2017 scalp 20–65 Cetirizine:67
Placebo:18
NA androgenetic alopecia 6 m NA 1 mL Placebo:2.59 ± 0.55 global photographic NA Cetirizine:30.31 ± 4.21
Ulrike Blume-Peytavi et al. 2012 scalp 23 to 35 Latanoprost:16
Placebo:16
mild androgenetic alopecia 24 w 1 0.05 mL Placebo:0.10 global photographic Latanoprost:6
Placebo:1
Latanoprost:0.22
Mohammadreza Rafati et al. 2022 scalp Latanoprost:29.2 ± 9.8
Placebo:29.8 ± 12.1
Latanoprost:12 Placebo:12 NA alopecia areata 12 w 1 0.25 mL Placebo:14.6 ± 18.6 global photographic the same between groups Latanoprost:37.2 ± 26.1
Mark Borchert et al. 2016 eyelash Bimatoprost:14.5
Placebo:14.6
Bimatoprost:48
Placebo:23
GEA < 3 multiple factors 4 m 1 0.05 mL Placebo:0.79 digital image analysis Bimatoprost:12
Placebo:0
Bimatoprost:1.21
Jean Carruthers et al. 2016 eyebrow Bimatoprost BID:53.5 ± 10.82
Bimatoprost QD:55.0 ± 11.11
Placebo:53.5 ± 9.8
Bimatoprost BID:118
Bimatoprost QD:118
Placebo:121
GEBA≤2 NA 7 m 1 or 2 0.05 mL Placebo:6.42 digital image analysis Bimatoprost BID:42
Bimatoprost QD:48
Placebo:41
Bimatoprost:

GEA, Global Eyelash Assessment; GEBA, Global Eyebrow Assessment; QD, Bimatoprost once daily; BID, Bimatoprost twice daily.