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. 2023 Mar 14;14:1148411. doi: 10.3389/fendo.2023.1148411

Table 4.

Clinical outcomes following transfer of vitrified cleavage embryos in different storage duration groups.

Storage Groups I II III IV P-value
Storage duration (months) 1-6 7-12 13-36 37-84
No. of cycles 289 108 80 54
Mean storage duration (months) 3.63 ± 1.50 9.06 ± 1.75 23.36 ± 7.62 52.22 ± 11.86
Age at FET (years) 31.93 ± 3.75 32.42 ± 3.43 33.15 ± 3.65 33.69 ± 3.00 0.002
Endometrial thickness (mm) 9.92 ± 1.81 9.43 ± 1.83 9.96 ± 1.88 9.98 ± 1.86 0.081
Number of embryos transferred 2.31 ± 0.62 2.33 ± 0.60 2.25 ± 0.56 1.91 ± 0.62 P<0.001
Number of good-quality embryos transferred 1.73 ± 0.65 1.79 ± 0.64 1.73 ± 0.66 1.48 ± 0.54 0.032
Biochemical pregnancy rate 14 (4.8%) 3 (2.8%) 1 (1.3%) 3 (5.6%) 0.412
Implantation rate 155/667 (23.2%) 63/252 (25.0%) 43/180 (23.9%) 32/103 (31.1%) 0.384
Clinical pregnancy rate 118 (40.8%) 51 (47.2%) 34 (42.5%) 22 (40.7%) 0.710
Ongoing pregnancy rate 93 (32.2%) 44 (40.7%) 27 (33.8%) 19 (35.2%) 0.461
Live birth rate 91 (31.5%) 42 (38.9%) 26 (32.5%) 18 (33.3%) 0.579
Miscarriage rate 20 (16.9%) 6 (11.8%) 8 (23.5%) 2 (9.1%) 0.395
Multiple pregnancy rate 37 (31.4%) 12 (23.5%) 9 (26.5%) 9 (40.9%) 0.462
Ectopic pregnancy rate 7 (5.9%) 2 (3.9%) 0 (0.0%) 1 (4.5) 0.600

Data are mean ± SD, n (%) or n/N (%).