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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1991 Mar;50(3):178–181. doi: 10.1136/ard.50.3.178

Protein losing enteropathy associated with collagen diseases.

A Tsutsumi 1, T Sugiyama 1, R Matsumura 1, M Sueishi 1, K Takabayashi 1, T Koike 1, H Tomioka 1, S Yoshida 1
PMCID: PMC1004370  PMID: 2015012

Abstract

Four patients with collagen diseases are described, who developed protein losing enteropathy in the course of their disease. Their protein losing enteropathies subsided after treatment with 60 mg/day oral prednisolone. Immunohistological studies of the small intestine showed deposits of C3 in the capillary walls of villi in two patients. Increased capillary permeability due to autoimmune phenomena may have a role in the pathogenesis of protein losing enteropathy associated with collagen diseases.

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Selected References

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  1. Casteñeda S., Maldenhauen F., Herrero-Beaumont G., Yañez R. Protein losing enteropathy as the initial manifestation of systemic lupus erythematosus. J Rheumatol. 1985 Dec;12(6):1210–1212. [PubMed] [Google Scholar]
  2. Chase G. J., O'Shea P. A., Collins E., Brem A. S. Protein-losing enteropathy in systemic lupus erythematosus. Hum Pathol. 1982 Nov;13(11):1053–1055. doi: 10.1016/s0046-8177(82)80102-0. [DOI] [PubMed] [Google Scholar]
  3. Heck L. W., Alarcón G. S., Ball G. V., Phillips R. L., Kline L. B., Moreno H., Hirschowitz B. I., Baer A. N., Dessypris E. N. Pure red cell aplasia and protein-losing enteropathy in a patient with systemic lupus erythematosus. Arthritis Rheum. 1985 Sep;28(9):1059–1061. doi: 10.1002/art.1780280914. [DOI] [PubMed] [Google Scholar]
  4. Hopkins P., Belmont H. M., Buyon J., Philips M., Weissmann G., Abramson S. B. Increased levels of plasma anaphylatoxins in systemic lupus erythematosus predict flares of the disease and may elicit vascular injury in lupus cerebritis. Arthritis Rheum. 1988 May;31(5):632–641. doi: 10.1002/art.1780310508. [DOI] [PubMed] [Google Scholar]
  5. Hugli T. E. Structure and function of the anaphylatoxins. Springer Semin Immunopathol. 1984;7(2-3):193–219. doi: 10.1007/BF01893020. [DOI] [PubMed] [Google Scholar]
  6. Itoi K., Sasaki T., Sawai T., Nakamura M., Hiwatashi N., Muryoi T., Yokoyama N., Yoshinaga K. Protein-losing gastroenteropathy in association with immune deposits in gastrointestinal mucosal capillaries. Am J Gastroenterol. 1989 Feb;84(2):187–191. [PubMed] [Google Scholar]
  7. Marks J., Birkett D. A., Shuster S. "Capillary permeability" in patients with collagen vascular diseases. Br Med J. 1972 Mar 25;1(5803):782–784. doi: 10.1136/bmj.1.5803.782. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Monballyu J., Hauglustaine D., Geboes K., Desmet V., Michielsen P. Protein-losing enteropathy in systemic lupus erythematosus. Digestion. 1985;31(4):243–246. doi: 10.1159/000199206. [DOI] [PubMed] [Google Scholar]
  9. Pachas W. N., Linscheer W. G., Pinals R. S. Protein-losing enteropathy in systemic lupus erythematosus. Am J Gastroenterol. 1971 Feb;55(2):162–167. [PubMed] [Google Scholar]
  10. Pereira A. S., Pereira Filho R. A., Trevisan M. A., Magalhães A. F. Intestinal lymphangiectasia in systemic lupus erythematosus. Arq Gastroenterol. 1980 Oct-Dec;17(4):210–212. [PubMed] [Google Scholar]
  11. Takagi S., Oshimi K., Sumiya M., Gonda N., Kano S., Takaku F. Protein-losing enteropathy in systemic lupus erythematosus. Am J Gastroenterol. 1983 Mar;78(3):152–154. [PubMed] [Google Scholar]
  12. Tan E. M., Cohen A. S., Fries J. F., Masi A. T., McShane D. J., Rothfield N. F., Schaller J. G., Talal N., Winchester R. J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982 Nov;25(11):1271–1277. doi: 10.1002/art.1780251101. [DOI] [PubMed] [Google Scholar]
  13. Trentham D. E., Masi A. T. Systemic lupus erythematosus with a protein-losing enteropathy. JAMA. 1976 Jul 19;236(3):287–288. [PubMed] [Google Scholar]
  14. Tsukahara M., Matsuo K., Kojima H. Protein-losing enteropathy in a boy with systemic lupus erythematosus. J Pediatr. 1980 Nov;97(5):778–780. doi: 10.1016/s0022-3476(80)80266-6. [DOI] [PubMed] [Google Scholar]
  15. Weiser M. M., Andres G. A., Brentjens J. R., Evans J. T., Reichlin M. Systemic lupus erythematosus and intestinal venulitis. Gastroenterology. 1981 Sep;81(3):570–579. [PubMed] [Google Scholar]
  16. Wood M. L., Foulds I. S., French M. A. Protein losing enteropathy due to systemic lupus erythematosus. Gut. 1984 Sep;25(9):1013–1015. doi: 10.1136/gut.25.9.1013. [DOI] [PMC free article] [PubMed] [Google Scholar]

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