Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparative result from molecular docking results of the wild type and the double mutant form with linoleic acid and selected hits (selexipag and pralatrexate)
| Ligand name | Docking score | |
|---|---|---|
|
| ||
| Variant reported in PDB: 6ZB4 (unmutated form) | Double mutated variant | |
| LA | −7.540 | 7.152 |
| Selexipag | −11.463 | −12.189 |
| Pralatrexate | −10.758 | −9.504 |
LA=Linoleic acid, PDB=Protein data bank
