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. 2023 Mar 28;14:1734. doi: 10.1038/s41467-023-37422-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Scatter dot charts show the neutralization potency, reported as IC₁₀₀ (ng ml⁻¹), of nAbs tested against the original Wuhan SARS-CoV-2 virus, and the Omicron BA.1, BA.2, BA.4 and BA.5 lineages for SN2 (a), SN3 (b), and SP2 (c), respectively. The number, percentage, GM-IC₁₀₀ (black lines and colored bars), fold-change and statistical significance of nAbs are denoted on each graph. Reported fold-change and statistical significance are in comparison with the Wuhan virus. Technical duplicates were performed for each experiment. d The table shows the IC₁₀₀ geometric mean (GM-IC₁₀₀) of all nAbs pulled together from SN2, SN3 and SP2 against all SARS-CoV-2 viruses tested. A nonparametric Mann–Whitney t test was used to evaluate statistical significances between groups. Two-tailed p value significances are shown as *p < 0.05, **p < 0.01, and ***p < 0.001. Source data are provided as a Source Data file.