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. 2023 Feb 21;12(3):429. doi: 10.3390/antibiotics12030429

Table 3.

Generalized linear mixed model for quarter level bacteriological cure during the DP 1.

Effect Odds Ratio SE 2 t-Value p-Value 95% CI 3 for Odds Ratio
Lower Upper
Intercept 2.296 0.2992 2.778 0.006 1.277 4.128
pathogen category
S. aureus 4 4.711 0.4059 3.819 <0.001 2.126 10.442
NAS 5 1.589 0.2582 1.794 0.073 0.958 2.637
streptococci 9.229 0.5440 4.086 <0.001 3.176 26.814
Coliforms 3.527 0.3803 3.314 <0.001 1.673 7.433
other Gram-negative bacteria 2.339 0.5808 1.463 0.144 0.749 7.305
other Gram-positive bacteria 20.100 0.5583 5.375 <0.001 6.727 60.063
non-bacterial pathogens 2,490,297.566 1056.0896 0.014 0.989 0.000 0.000
mixed infections Reference
season of DO 6
Winter 1.423 0.2123 1.663 0.097 0.939 2.158
Spring 0.696 0.1715 −2.116 0.034 0.497 0.974
Summer 0.911 0.1503 −0.617 0.537 0.679 1.224
Autumn Reference
DCT 7
Non-AB 8 0.925 0.2872 −0.270 0.787 0.527 1.625
AB Reference
Interaction of DCT and pathogen category
Non-AB DCT in combination with each pathogen category:
S. aureus 0.453 0.4795 −1.653 0.098 0.177 1.159
NAS 0.720 0.3187 −1.030 0.303 0.385 1.345
streptococci 0.140 0.6002 −3.274 0.001 0.043 0.455
Coliforms 1.932 0.5772 1.141 0.254 0.623 5.991
other Gram-negative bacteria 1,311,544.105 378.3516 0.037 0.970 0.000 0.000
other Gram-positive bacteria 0.126 0.5976 −3.468 <0.001 0.039 4.06
non-bacterial pathogens 1.009 1174.0970 0.000 1.000 0.000 0.000
corresponding AB group 9 Reference

1 dry period; 2 Standard error; 3 Confidence Interval; 4 Staphylococcus aureus; 5 non-aureus staphylococci; 6 dry off; 7 dry cow treatment; 8 antibiotic; 9 non-AB DCT was compared to AB DCT within each pathogen category, thus, the Reference to non-AB DCT for one pathogen category is the matching AB treatment group for the same pathogen category.