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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: Environ Res. 2022 Dec 30;220:115188. doi: 10.1016/j.envres.2022.115188

Table 6.

Comparison of IARC, NTP, and UCB chronic inflammation/immunosuppression search results for PFASs, chromium (VI), and benzene.

PubMed Search Result Unique Resulta Overlapped with UCB
Search IARC NTP UCB IARC NTP
 UCB IARC NTP IARC/NTP
Crudeb Relevantc
PFASs
Chronic inflammation 94 128 532 1 28 1 379 93 96 33
Immunosuppression 162 241 998 0 143 0 775 162 97 32
Both 248 361 1155 0 161 1 795 248 195 77
Total relevant resultsd 127 85 349* – – – – – – –
Chromium (VI)e
Chronic inflammation 31 27 317 0 4 0 274 31 23 11
Immunosuppression 90 263 514 0 177 7 374 90 85 35
Both 118 289 564 0 173 1 380 118 115 49
Benzenee,f
Chronic inflammation 69 125 1304 2 37 1 1178 67 88 29
Immunosuppression 170 525 1848 0 366 1 1564 170 159 45
Both (new) 225 641 1951 0 386 2 1554 225 255 83
a

Only unique IARC and NTP results were assessed for relevancy in SysRev.

b

These numbers are the crude numbers for NTP’s unique result after uploading the PMID files into SysRev.

c

Relevant studies identified from unique IARC and NTP results via title/abstract screen.

d

Total relevant results are only for PFAS search results assessed during title/abstract screen and are compared to search results for both KCCs. (*This is the number of studies we assessed for full-text secondary screening; see Fig. 2).

e

Our search results are the crude number generated from PubMed and have not yet been subject to screening.

f

Search results for benzene are based on human studies only.