Table 3.
Effect of the specific surface of PCL, PLGA, and PLCL scaffolds on degradation.
Polymer | PCL | PLGA | PLCL | ||||||
---|---|---|---|---|---|---|---|---|---|
Form-factor | Rod | Film | Fibrous material | Rod | Film | Fibrous material | Rod | Film | Fibrous material |
Dimensions | ⌀ 1.7 mm | Thickness 0.1 mm | ⌀ 0.0016 mm | ⌀ 2.3 mm | Thickness 0.1 mm | ⌀ 0.0049 mm | ⌀ 2.5 mm | Thickness 0.2 mm | ⌀ 0.0036 mm |
Specific surface area, m2/g | 0.002 | 0.016 | 2.1 | 0.0013 | 0.016 | 0.62 | 0.0012 | 0.008 | 0.88 |
Original Mn, kDa | 96 | 50 | 111 | 63 | 58 | 69 | 91 | 36.6 | 54 |
Crystallinity, % | 64 | 58 | 35 | 75:25 | 75:25 | 70:30 | 70:30 | 74:26 | 70:30 |
Mn decreasing after 140 days in PBS at 37 °C, % | 0 | 11 | 36 | 52 | 38 | 15 | 40 | 52 | 14 |
Mn decreasing after 140 days in DMEM at 37 °C, % | - | 25 | 86 | 94 | 86 | 68 | 89 | - | 62 |
Reference | [69] | [101] | - | [101] | [102] | - | [102] | [103] | - |