Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Mar 6;12(3):651. doi: 10.3390/antiox12030651

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Role of free radicals on oxidative stress and the aging process. Various endogenous and exogenous factors can generate free radicals/oxidants, affecting the antioxidant defenses, which promote oxidative stress that can damage different biomolecules. The damaged biomolecules affect inter and intracellular signaling and gene expression pathways, causing several cell alterations. The interplay between these events can lead to aging, which increases aging-associated syndromes and aging-related diseases. Antioxidant supplementation can retard the aging process.