Table 2.
Comparison of APTw and DKI-derived parameters among different histopathological parameters of cervical cancer.
| Variables | APTw (%) | p | MK | p | MD (×10−3 mm2/s) | p | |
|---|---|---|---|---|---|---|---|
| Lymph node status | <0.001 | 0.005 | 0.035 * | ||||
| Non-LNM (n = 44) | 2.4 ± 1.0 | 0.909 ± 0.189 | 1.193 ± 0.337 | ||||
| LNM (n = 17) | 3.7 ± 1.1 | 1.065 ± 0.185 | 0.989 ± 0.195 | ||||
| Tumor size | 0.319 | 0.009 | 0.005 * | ||||
| <4 cm (n = 39) | 2.6 ± 1.2 | 0.903 ± 0.191 | 1.219 ± 0.336 | ||||
| ≥4 cm (n = 22) | 3.0 ± 1.1 | 1.040 ± 0.187 | 0.990 ± 0.213 | ||||
| Histological classification | 0.447 | 0.471 | 0.014 * | ||||
| CSC (n = 52) | 2.8 ± 1.2 | 0.960 ± 0.191 | 1.076 ± 0.230 | ||||
| CA (n = 9) | 2.5 ± 1.2 | 0.908 ± 0.247 | 1.485 ± 0.501 | ||||
| FIGO stage | 0.002 | <0.001 | <0.001 * | ||||
| Early-stage (n = 32) | 2.3 ± 1.0 | 0.857 ± 0.186 | 1.285 ± 0.345 | ||||
| Advanced-stage (n = 29) | 3.2 ± 1.1 | 1.058 ± 0.157 | 0.973 ± 0.171 | ||||
| Histological grade | 0.117 | 0.016 | 0.142 * | ||||
| Low grade (n = 32) | 2.5 ± 1.0 | 0.895 ± 0.195 | 1.193 ± 0.371 | ||||
| High grade (n = 29) | 3.0 ± 1.2 | 1.016 ± 0.187 | 1.074 ± 0.232 | ||||
| Depth of invasion | 0.001 | <0.001 | 0.011 * | ||||
| <2/3 of cervical wall (n = 27) |
2.2 ± 0.9 | 0.845 ± 0.175 | 1.270 ± 0.381 | ||||
| ≥2/3 of cervical wall (n = 34) |
3.2 ± 1.2 | 1.038 ± 0.176 | 1.031 ± 0.202 | ||||
| Vascular invasion | 0.140 | 0.210 | 0.394 * | ||||
| No (n = 44) | 2.6 ± 1.0 | 0.933 ± 0.215 | 1.132 ± 0.345 | ||||
| Yes (n = 17) | 3.1 ± 1.4 | 1.004 ± 0.142 | 1.148 ± 0.234 | ||||
* Mann–Whitney U test; others are Students’ t-test. Bold type face in the table indicates that the comparison is statistically significant. APTw = amide proton transfer-weighted; MK = mean kurtosis; MD = mean diffusivity; LNM= lymph node metastasis; Non-LNM = non-lymph node metastasis; CSC = cervical squamous carcinoma; CA = cervical adenocarcinoma; FIGO = International Federation of Gynecology and Obstetrics.