Figure 5.

As seen in the figure scale, regions highlighted in bright green would be indicative of consistent and significant evidence supporting an inverse relationship between vitamin E supplementation and cancer risk, but no such systems exist. Pale green regions represent systems in which there is mixed evidence supporting an inverse relationship between vitamin E supplementation and cancer risk, as well as evidence supporting no relationship between vitamin E supplementation and cancer risk. Pale green regions indicate these findings for breast, lung, and colorectal tissue. Grey regions signify consistent evidence supporting no relationship between vitamin E supplementation and cancer risk. Grey regions indicate these findings for pancreatic and bladder tissue. Pale red regions represent systems in which there is mixed evidence supporting a relationship between vitamin E supplementation and increased cancer risk, as well as evidence supporting no relationship between vitamin E supplementation and cancer risk. The pale red region indicates these findings for prostatic tissue. Lastly, regions highlighted in bright red would be indicative of consistent and significant evidence supporting a relationship between vitamin E supplementation and increased cancer risk; however, no such systems exist.