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. 2023 Mar 7;11(3):818. doi: 10.3390/biomedicines11030818

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Correlation analysis of cytokine levels and ccf-mtDNA units. (a–d) Correlation analysis of plasma IL-12p70 and MCP-1 levels with those of ND4 and CO1 units in males. (e–h) Correlation analysis of plasma IL-12p70 and MCP-1 levels with those of ND4 and CO1 units in females. (i) Clustering heatmap analysis for correlation of the cytokines IL-12p70 and MCP-1 and the genes ND4 and CO1 units in all the samples, and separated by sex. (* High correlation 0.6 < |r| ≤ 0.8, ** very high correlation 0.8 < |r| ≤ 1.0.)