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. 2023 Mar 20;12(3):757. doi: 10.3390/antiox12030757

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Nanoceria reduced DNA damage and prevented mutagenesis in HaCaT cells. (A) Comet assay analysis of UVB-irradiated HaCaT ± nanoceria (CNPs). Values are normalized with respect to the maximum value (UVB 1h) posed = 1. Statistical significance was calculated via Student’s t-test. ** p < 0.01, with respect to UVB-irradiated cells. (B) Micronuclei after UVB exposure ± nanoceria (CNPs). Nanoceria pretreatment halves UVB-induced micronuclei. Statistical significance was calculated via Student’s t-test. * p < 0.05 and ** p < 0.001 with respect to UVB-irradiated cells.