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. 2023 Mar 22;12(3):488. doi: 10.3390/biology12030488

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Glioma patients with DEMPERGs were distinguished into two subgroups via unsupervised consensus clustering with differences in survival and function. (A) Consensus CDF curve of two to six clusters. (B) Relative area changes under the CDF curve from k = 2 to 6. (C) Complex heatmap of the DEMPERG expression in two clusters. (D) DEMPERG expression between the two clusters. (E) PCA plot. (F) KM OS plot. (G) Volcano plot of the cluster-associated genes. (H) Ridge plots of the GSEA. Yellow and blue words represent immune− and cancer−stemness−associated pathways, respectively.