Table 1.
Lipid reprogramming in RCC tumors | Mechanism | References |
---|---|---|
Decreased cholesterol biosynthesis | 59,65 | |
Increased cholesterol uptake | 78,81,82 | |
Increased fatty acid biosynthesis | 82,88,89,92,94,95 | |
Increased fatty acid uptake | 98,99 | |
Reduced fatty acid catabolism | 101 | |
Reduced Lipolysis | 125 | |
LDs Accumulation | HIF-α stabilization | 101,129,130 |