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. 2023 Mar 14;14:1113194. doi: 10.3389/fimmu.2023.1113194

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Copyright © 2023 Oluka, Namubiru, Kato, Ankunda, Gombe, Cotten, The COVID-19 Immunoprofiling Team, Musenero, Kaleebu, Fox and Serwanga

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Shows scatter plots and lines of best fit for S-IgG (A) and S-IgA (B) following calibration of the WHO standard (WHO) against the assay commercial standard (STD). After analyzing the parallelism and linearity of the WHO and secondary standards linear models, a linear regression analysis was fitted to convert concentration in ng/ml to BAU/ml. Dilutional linearity was computed using a linear regression model to show the ability of the assay to provide results (Concentration(ng/ml) that are directly proportional to the expected Concentrations (ng/ml) at the various dilutions (C).