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. 2023 Mar 27;23:161. doi: 10.1186/s12872-023-03150-w

Table 2.

Clinical characteristics and laboratory results in age adjusted quartiles (Q) of waist:height ratio

Variable Q1 Q2 Q3 Q4 Range (all quartiles)
Hemoglobin (g/l) 142 (12) 144 (12) 146 (11) 145 (12) 113–177
Sodium (mmol/l) 140.7 (2.0) 140.2 (2.1) 140.3 (1.9) 140.3 (1.9) 134–146
Potassium (mmol/l) 3.82 (0.27) 3.75 (0.26) 3.83 (0.26) 3.85 (0.30)† 3.2–4.9
Calcium (mmol/l) 2.30 (0.11) 2.29 (0.10) 2.32 (0.12) 2.30 (0.10) 2.07–2.74
Parathyroid hormone (pmol/l) 4.4 (1.7) 4.3 (1.4) 4.5 (1.6) 5.0 (2.1)*†‡ 1.4–9.9
 C-reactive protein (mg/l) 0.6 [0.5-1.0] 0.6 [0.5–1.3] 1.0 [0.5–1.7]* 1.9 [0.8–3.1]*†‡ 0.1–17.9
Uric acid (µmol/l) 277 (73) 287 (72) 313 (76)*† 328 (77)*† 103–600
Creatinine (µmol/l) 76 (14) 75 (14) 74 (13) 71 (14)* 42–116
Cystatin C (mg/l) 0.82 (0.14) 0.82 (0.16) 0.86 (0.14)* 0.87 (0.13)*† 0.47–1.31
Estimated GFR (ml/min/1.73m2) 102 (17) 102 (19) 97 (18) 96 (17)* 53–152
Leptin (ng/ml) 8.6 (8.5) 12.1 (9.2) 15.9 (12.8)* 28.0 (20.1)*†‡ 0.2–92.3
Adiponectin (µg/ml) 4.3 (2.4) 3.9 (1.6) 3.4 (1.7)* 3.5 (1.7)* 0.5–18.2
Renin activity (ng Ang I/ml/h) 0.8 [0.5–1.3] 0.8 [0.4–1.3] 0.7 [0.4–1.3] 0.6 [0.4–1.1] 0.1–10.0
Aldosterone (pmol/l) 436 [306–636] 434 [329–581] 459 [338–595] 416 [304–539] 68-1704
Aldosterone:renin ratio 597 [398–791] 634 [383–884] 640 [430–948] 632 [389–979] 45-2701
Fasting plasma
   Total cholesterol (mmol/l) 4.9 (1.0) 4.9 (1.0) 5.3 (1.1)*† 5.4 (1.0)*† 2.5-9.0
   Triglycerides (mmol/l) 0.9 [0.6–1.2] 1.0 [0.7–1.3] 1.1 [0.8–1.5]* 1.2 [1.0–2.0]*† 0.3–5.5
   HDL cholesterol (mmol/l) 1.8 (0.5) 1.6 (0.4)* 1.5 (0.4)* 1.4 (0.4)*† 0.7–3.1
   LDL cholesterol (mmol/l) 2.8 (0.9) 2.8 (0.9) 3.2 (0.9)*† 3.3 (0.9)*† 0.8–5.8
   Insulin (mU/l) 6.0 (3.6) 6.9 (4.7) 8.2 (5.3)* 11.5 (7.9) *†‡ 1.0-51.8
   Glucose (mmol/l) 5.3 (0.5) 5.4 (0.5) 5.5 (0.5)* 5.7 (0.8)*†‡ 4.1–7.5
QUICKI 0.380 (0.056) 0.366 (0.036)* 0.354 (0.032)* 0.338 (0.033)*†‡ 0.268–0.740

Results shown as mean (standard deviation) or median [25th -75th percentile]; BP, blood pressure; estimated GFR, estimated glomerular filtration rate based on cystatin C (CKD-EPI) [45]; QUICKI, quantitative insulin sensitivity check index [28]; *P < 0.05 vs. Q1; †P < 0.05 vs. Q2; ‡P < 0.05 vs. Q3