Fig 2. HAPLN1-PTR1 causes RPMI8226 MM cell resistance to different classes of therapeutic agents.

RPMI8226 cells were cultured with 100 nM GST-PTR1 (H1-P1) or GST (-) in the presence or absence of indicated drugs at 50–80% cytotoxicity and the cell viability was measured as described in Materials and Methods. Results represent the mean ± SD of three biological replicates, each performed in triplicate. * p<0.05, ** p<0.01.