Table 1.
Comparison of basal parameters between the WT and LMP2-KO rats
| Item | WT rats | LMP2-KO rats | P value | Item | WT rats | LMP2-KO rats | P value |
|---|---|---|---|---|---|---|---|
| Heart rate | 374.47 ± 43.65 | 384.42 ± 50.49 | 0.574 | LDL-C (mmol/L) | 3.24 ± 0.89 | 4.29 ± 0.98 | 0.023 |
| Systolic pressure (mmHg) | 123.67 ± 16.14 | 128.43 ± 9.85 | 0.350 | Uric acid (umol/L) | 474.80 ± 85.61 | 552.96 ± 65.79 | 0.034 |
| Diastolic pressure (mmHg) | 94.33 ± 12.35 | 94.42 ± 11.17 | 0.983 | Blood glucose (mmol/L) | 8.94 ± 1.21 | 12.68 ± 2.62 | 0.001 |
| White blood cell count (× 109/L) | 7.38 ± 2.94 | 7.46 ± 1.16 | 0.962 | ALT (U/L) | 45.57 ± 9.60 | 40.34 ± 9.92 | 0.246 |
| Number of lymphocytes (× 109/L) | 4.36 ± 0.91 | 4.94 ± 1.55 | 0.492 | Total cholesterol (mmol/L) | 2.82 ± 0.64 | 3.05 ± 0.76 | 0.478 |
| Concentration of hemoglobin (g/L) | 160.80 ± 12.68 | 135.20 ± 42.45 | 0.232 | Creatinine (umol/L) | 53.89 ± 23.70 | 54.14 ± 22.30 | 0.975 |
| Number of platelets (× 109/L) | 690.60 ± 347.83 | 688.60 ± 446.56 | 0.994 |