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. 2023 Mar 17;5(2):otad016. doi: 10.1093/crocol/otad016

Table 2.

Univariate and multivariate regressions for moderate–high risk of sleep apnea (OSA-50 > 5) considering demographic data, IBD medications, depression, anxiety, and IBD data.

Univariate regression (odds ratio, confidence interval, P value) Multivariate regression (odds ratio, confidence interval, P value)
Age 1.05 (1.04–1.07), P < .001 1.06 (1.04–1.08), P < .001
Male gender 1.28 (0.83–1.99), P = .27
Crohn’s disease 0.90 (0.61–-1.33), P = .60
Disease duration 1.01 (0.99–1.03), P = .096
Previous surgery for IBD 1.28 (0.84–1.96), P = .24
Current steroid use 1.38 (0.75–2.54), P = .302
Current biologic use 1.17 (0.80–1.72), P = .41
Current immunomodulator use 1.18 (0.79–1.74), P = .42
Obesity 5.39 (3.58–8.10), P < .001 6.42 (4.08–10.10), P < .001
Smoking 2.52 (1.31–4.81), P = .005 2.60 (1.26–5.39), P = .010
Alcohol usage 1.16 (0.78–1.73), P = .45
Opioid usage 1.55 (0.94–2.55), P = .082
Medications for sleep 0.98 (0.57–1.70), P = .95
Clinically significant depression 1.76 (1.13–2.75), P = .013
Clinically significant anxiety 0.92 (0.61–0.139), P = .69
Abdominal pain subscore 1.33 (1.09–1.62), P = .004 1.32 (1.05–1.65), P = .017
Nocturnal diarrhea subscore 2.11 (1.11–3.99), P = .022
Clinically active IBD 1.73 (1.01–2.93), P = .044

Abbreviations: IBD, inflammatory bowel disease; OSA, obstructive sleep apnea.