Table 2.

Fatigue severity scale before and after 6 months of levothyroxine replacement therapy.

Item	Before Levothyroxine	After 6 Months of Levothyroxine	p Value
1. My motivation is lower when I am fatigued	7 (6–7)	4 (3–5)	0.001 *
2. Exercise brings on my fatigue	7 (2–7)	4 (1–5)	0.004 *
3. I am easily fatigued	6 (5–7)	4 (1–5)	0.002 *
4. Fatigue interferes with my physical functioning	6 (5–7)	4 (1–5)	0.001 *
5. Fatigue causes frequent problems for me	6 (5–7)	4 (1–6)	0.007 *
6. My fatigue prevents sustained physical functioning	7 (5–7)	3 (1–5)	0.001 *
7. Fatigue interferes with carrying out certain duties and responsibilities	7 (5–7)	3 (2–5)	0.001 *
8. Fatigue is among my three most disabling symptoms	7 (6–7)	4 (2–6)	0.001 *
9. Fatigue interferes with my work, family, or social life	3 (1–5)	1 (1–3)	0.001 *
Total	53 (47–57)	36 (16–38)	0.001 *

Quantitative variables were reported as median and interquartile range. * p > 0.05 = statistical significance.