Table 3.
Changes in Paw Diameter Experimental Animals (Mean ± SEM) | ||||||
---|---|---|---|---|---|---|
Tested Sample | Dosage | 1 h | 2 h | 3 h | Aver. Paw Diameter | % Inhibition |
Carrageenan | 1 mL | 1.18 ± 0.06 | 1.46 ± 0.02 | 1.81 ± 0.02 | 1.48 ± 0.01 | --- |
Normal saline | 1 mL | 1.15 ± 0.05 | 1.43 ± 0.02 | 1.77 ± 0.05 | 1.45 ± 0.03 | --- |
Diclofenac sodium | 50 mg/kg | 0.47 ± 0.03 | 0.41 ± 0.04 | 0.30 ± 0.02 | 0.39 ± 0.06 | 73.64 |
EO | 25 | 0.75 ± 0.04 | 0.66 ± 0.03 | 0.59 ± 0.04 | 0.66 ± 0.02 * | 55.40 |
50 | 0.71 ± 0.02 | 0.62 ± 0.04 | 0.51 ± 0.03 | 0.61 ± 0.05 * | 58.78 | |
100 | 0.57 ± 0.05 | 0.51 ± 0.03 | 0.45 ± 0.05 | 0.51 ± 0.04 * | 65.54 |
Carrageenan inducer of paw edema, normal saline as a negative control, and diclofenac sodium was used as a standard, EO essential oil with p ≤ 0.05 *.