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. 2023 Mar 16;12(3):729. doi: 10.3390/antiox12030729

Figure 5.

Figure 5

Immunohistochemistry in kidney medullary tissues from control and STZ female and male mice. Arrows indicate glomeruli. After 6 days of single STZ administration, NOX-4 (green color) was significantly augmented in cortical (glomeruli and tubular structures) and medullary tissues (tubular and interstitial structures) from female STZ mice. This was less evident in males. Fibronectin immunostaining was more evident in STZ mice, while TGF-β1 was more evident in glomeruli and tubular cells in female and male STZ mice compared to controls.

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