Table 3.
Univariable and multivariable logistic regression analyses of plasma LRG1 for prediction of DD.
Variables | Unadjusted OR | p-Value | Adjusted OR | p-Value |
---|---|---|---|---|
[95% CI] | [95% CI] | |||
LRG1 | 1.26 | <0.001 | 1.32 ** | <0.001 |
[1.23–1.42] | [1.14–1.53] | |||
SYNTAX | 1.1 | - | 1.08 ** | 0.007 |
[1.06–1.16] | [1.02–1.14] | |||
Creatinine | 1.02 | - | 1.04 ** | 0.005 |
[1.01–1.04] | [1.01–1.06] | |||
DM | 3.41 | - | 6.93 ** | 0.006 |
[1.35–8.61] | [1.76–27.34] |
The odds ratio (OR) compared the probability for a positive DD diagnosis and is presented as unadjusted and adjusted for SYNTAX, creatinine, and DM, with 95% CI indicating clinical significance. p-values of ** p < 0.001 were statistically significant. The adjusted model (χ2(4) = 57.866, p < 0.001) explained 57.8% of the variance in DD and correctly classified 83% of cases. DD, diastolic dysfunction; OR, odd ratio; 95% CI, 95% confidence interval.