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. 2023 Mar 8;132(7):828–848. doi: 10.1161/CIRCRESAHA.122.321448

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© 2023 The Authors.

Circulation Research is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 2. — Analysis of the PDE3A1 (phosphodiesterase 3A1), PDE3A2, and PDE2A2 interactomes. A, Volcano plot of the PDE3A1-mCherry interactome (false discovery rate [FDR], 0.03; S-zero is the fold-change threshold [S0], 1.3). B, PDE3A2-mCherry interactome (FDR, 0.05; S0, 0.8). C, PDE2A2-mCherry interactome (FDR, 0.03; S0, 1.3). D, Area-proportional Venn diagram to compare significant interactors in PDE3A1, PDE3A2, and PDE2A2 affinity purifications.