Skip to main content
. 2023 Feb 24;13(3):434. doi: 10.3390/biom13030434

Figure 5.

Figure 5

Effects of baclofen on choroidal and retinal thickness in DM, LIM and LIH. Control eyes of DM chicks received baclofen or saline injections, while those of LIM or LIH chicks were not injected at all. Choroid and retina were significantly thinner in experimental eyes than in fellow eyes in DM (A,D) and LIM (B,E); baclofen injections had no additional effect. Baclofen however thinned the choroid in LIH (C). Treatment with positive lenses increased retinal thickness, but there was no additional effect of baclofen vs. saline on retinal thickness (F). There was no difference in cartilaginous nor fibrous layer thickness between experimental and fellow eyes in DM (G,J) or LIM (H,K) groups. Positive lens-wearing eyes had a thicker cartilaginous layer (I) and thinner fibrous layer (L) than fellow eyes. Data are shown as mean ± SEM. Difference between two groups were analyzed with two-way mixed ANOVA with Sidak’s post hoc test. Binocular differences were analyzed with paired t-test. ns: not significant; *: p < 0.05; **: p < 0.01; ***: p < 0.001.