Figure 6.

Dopamine and dopamine metabolite content. Control eyes of DM chicks received baclofen or saline injections, while those of LIM or LIH chicks were not injected at all. Baclofen significantly decreased the amount of vitreal DOPAC in all the baclofen-injected eyes (A–C), as well as vitreal dopamine level in deprived (D) and positive lens-treated eyes (F), but not in in negative lens-treated eyes (E). The level of vitreal HVA (H) and retinal DOPAC (K) in LIM eyes were reduced via baclofen, while there was no significant difference in deprived (G,J) and positive lens-treated eyes (I,L). Data show the mean ± SEM. Difference between two groups were analyzed with two-way mixed ANOVA with Sidak’s post hoc test. Binocular differences were analyzed with paired t-test. ns: not significant; *: p < 0.05; **: p < 0.01; ***: p < 0.001; ****: p < 0.0001.