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. 2023 Mar 2;8(1):101. doi: 10.3390/biomimetics8010101

Table 3.

The GRADE ranking of available evidence.

Certainty Assessment № of Patients Effect Certainty Importance
№ of Studies Study Design Risk of Bias Inconsistency Indirectness Imprecision Other Considerations TAD Other Treatment Methods Relative
(95% CI)
Absolute
(95% CI)
Overbite
10 Observational studies Not serious Serious a Not serious Not serious None 122 121 - MD 0.45 lower
(0.87 lower to 0.03 lower)
⨁⨁⨁◯
Moderate
Overjet
8 Observational studies Not serious Serious a Not serious Not serious a None 96 91 - MD 0.07 lower
(0.72 lower to 0.58 higher)
⨁⨁⨁◯
Moderate

CI: confidence interval; MD: mean difference. Explanations, a. The test of heterogeneity for this outcome is high.