Results from replication of comparative effectiveness study. Abbreviations: 1L: first line; ALK: anaplastic lymphoma kinase; EGFR: epidermal growth factor receptor; PD-L1: programmed death-ligand 1; ML: machine learning. (Panel (A)): Covariate balance plot, abstracted cohort. (Panel (B)): Covariate balance plot, ML-extracted cohort. (Panel (C)): Distribution of weights stratified by treatment group, abstracted cohort. (Panel (D)): Distribution of weights stratified by treatment group, ML-extracted cohort. (Panel (E)): Effect of treatment group on survival, stratified by data curation approach.