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. 2023 Mar 8;15(6):1670. doi: 10.3390/cancers15061670

Figure 2.

Figure 2

Figure 2

LR-IFN-β gavage ameliorates irradiation-induced changes in cytokine levels in the intestines: (A) IFN-γ; (B) IL-3; (C) IL-17. Five groups of mice (n = 3–4): control, irradiated (IR), IR plus intraperitoneal injection of IFN-β, IR plus intraoral 109 bacteria copies of L. reuteri (LR) in 200 µL of saline, and LR, with copies of LR-IFN-β in 200 µL of saline. Mice received their respective treatment 24 h after irradiation to 12 Gy TBI. Intestinal tissues were analyzed on day 5 after TBI. Values are mean ± SEM. Total body irradiation (TBI). Red type indicates a significant difference.