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Gene alterations and signaling pathways involved in breast cancer carcinogenesis and brain metastatic processes: estrogen, CoA: coactivators, EREs: estrogen receptor elements, NEC: Notch1 extracellular cell, NICD: Notch1 intracellular cell domain, CSL (CSL proteins): CBF-1/RBPJ-κ in Homo sapiens/Mus musculus, respectively, Suppressor of Hairless in Drosophila melanogaster, Lag-1 in Caenorhabditis elegans, PCNA: proliferating cell nuclear antigen.
