Table 3.
Clinical trials conducted/ongoing for validation of multi-cancer early detection tests.
| Trial ID | Trial Name | MCED Test | Sponsor | Status (as of July 2022) |
|---|---|---|---|---|
| NCT02889978 | CCGA | Galleri | GRAIL, LLC | Active, not recruiting |
| NCT03085888 | STRIVE | Galleri | GRAIL, LLC | Active, not recruiting |
| NCT03934866 | SUMMIT | Galleri | University College London and GRAIL | Active, not recruiting |
| NCT04241796 | PATHFINDER | Galleri | GRAIL, LLC | Active, not recruiting |
| NCT05155605 | PATHFINDER 2 | Galleri | GRAIL, LLC | Recruiting |
| NCT05205967 | REFLECTION | Galleri | GRAIL, LLC | Recruiting |
| NCT05235009 | LEV87A | GAGome | Elypta | Recruiting |
| NCT05295017 | LEV93A | GAGome | Elypta | Recruiting |
| NCT05227534 | PREVENT | OverC | Guangzhou Burning Rock Dx | Recruiting |
| NCT04825834 | DELFI-L101 | DELFI | Delfi Diagnostics Inc. | Recruiting |
| NCT04213326 | ASCEND | CancerSEEK | Exact Sciences | Completed |
| NCT03756597 | PAN | ReCIVA | Owlstone Ltd. | Unknown |
| NCT03517332 | -- | DEEPGEN | Quantgene Inc. | Unknown |
| NCT03967652 | -- | Na-nose | Anhui Medical University | Not yet recruiting |
| NCT05366881 | CAMPERR | -- | Adela, Inc. | Recruiting |
| NCT05254834 | Vallania | -- | Freenome Holdings Inc. | Recruiting |
| NCT04972201 | PROMISE | -- | Chinese Academy of Medical Sciences (and Burning Rock Dx) | Recruiting |
| NCT04822792 | PRESCIENT | -- | Chinese Academy of Medical Sciences (and Burning Rock Dx) | Recruiting |
| NCT04820868 | THUNDER | -- | Shanghai Zhongshan Hospital (and Burning Rock Dx) | Recruiting |
| NCT04817306 | PREDICT | -- | Shanghai Zhongshan Hospital (and Burning Rock Dx) | Recruiting |
| NCT05227261 | K-DETEK | -- | Gene Solutions | Recruiting |
| NCT05159544 | FuSion | -- | Singlera Genomics Inc. | Recruiting |
| NCT04405557 | PREDICT | -- | Geneplus-Beijing Co. | Active, not recruiting |
| NCT02662621 | EXODIAG | -- | Centre Georges Francois Leclerc | Completed |
| NCT04197414 | -- | -- | Yonsei University | Recruiting |
| NCT03951428 | -- | -- | LifeStory Health Inc. | Unknown |
| NCT03869814 | -- | -- | Bluestar Genomics Inc. | Active, not recruiting |
| NCT02612350 | -- | -- | Pathway Genomics | Completed |