n
|
|
103 |
41 |
|
Antiphospholipid antibodies (%)
|
No |
100 (97.1) |
41 (100.0) |
0.647 |
|
Yes |
3 (2.9) |
0 (0.0) |
|
Primary cancer organ (%)
|
Gynecological |
23 (22.3) |
0 (0.0) |
<0.001 |
|
Lung |
0 (0.0) |
41 (100.0) |
|
|
Other GIT cancers |
19 (18.4) |
0 (0.0) |
|
|
Others |
33 (32.0) |
0 (0.0) |
|
|
Pancreas |
28 (27.2) |
0 (0.0) |
|
Pathology (%)
|
Adenocarcinoma |
60 (58.3) |
33 (80.5) |
0.004 |
|
Hematopoietic |
6 (5.8) |
0 (0.0) |
|
|
Others |
34 (33.0) |
4 (9.8) |
|
|
Sarcoma |
1 (1.0) |
0 (0.0) |
|
|
SCC |
2 (1.9) |
4 (9.8) |
|
Adenocarcinoma vs. other pathologies (%)
|
Other pathologies |
43 (41.7) |
8 (19.5) |
0.02 |
|
Adenocarcinoma |
60 (58.3) |
33 (80.5) |
|
Organ of metastasis (n = 97) (%)
|
Bone |
3 (4.8) |
2 (5.9) |
0.258 |
|
Brain |
2 (3.2) |
1 (2.9) |
|
|
Liver |
20 (31.7) |
3 (8.8) |
|
|
Lung |
5 (7.9) |
2 (5.9) |
|
|
Lymph nodes |
11 (17.5) |
11 (32.4) |
|
|
Multiple |
15 (23.8) |
10 (29.4) |
|
|
Others |
7 (11.1) |
5 (14.7) |
|
Metastasis (n = 141) (%)
|
Non-metastatic |
38 (37.6) |
5 (12.8) |
0.008 |
|
Metastatic |
63 (62.4) |
34 (87.2) |
|
Marantic presentation before diagnosis of cancer (n = 125) (%)
|
Known cancer case |
34 (36.2) |
8 (25.8) |
0.401 |
|
Marantic as a first presentation |
60 (63.8) |
23 (74.2) |
|
Interval diagnosis (months) (mean (SD))
|
|
7.95 (29.56) |
1.54 (3.81) |
0.257 |
Age (median (IQR))
|
|
59.00 (49.00, 65.00) |
61.00 (55.00, 67.00) |
0.389 |
Sex (%)
|
F |
63 (61.2) |
18 (45.0) |
0.118 |
|
M |
40 (38.8) |
22 (55.0) |
|
COPD (n = 52) (%)
|
No |
39 (97.5) |
10 (83.3) |
0.254 |
|
Yes |
1 (2.5) |
2 (16.7) |
|
Smoke (n = 56) (%)
|
No |
37 (92.5) |
6 (37.5) |
<0.001 |
|
Yes |
3 (7.5) |
10 (62.5) |
|
Diabetes (n = 52) (%)
|
No |
31 (77.5) |
12 (100.0) |
0.17 |
|
Yes |
9 (22.5) |
0 (0.0) |
|
Obesity (n = 53) (%)
|
No |
40 (97.6) |
12 (100.0) |
1 |
|
Yes |
1 (2.4) |
0 (0.0) |
|
Dyslipidemia (n = 54) (%)
|
No |
35 (85.4) |
11 (84.6) |
1 |
|
Yes |
6 (14.6) |
2 (15.4) |
|
Hypertension (n = 56) (%)
|
No |
27 (64.3) |
9 (64.3) |
1 |
|
Yes |
15 (35.7) |
5 (35.7) |
|
Embolization event at presentation (n = 132) (%)
|
No |
12 (12.4) |
3 (8.6) |
0.767 |
|
Yes |
85 (87.6) |
32 (91.4) |
|
Embolic event after diagnosis (n = 125) (%)
|
No |
55 (59.1) |
21 (65.6) |
0.661 |
|
Yes |
38 (40.9) |
11 (34.4) |
|
Incidental finding of NBTE (%)
|
No |
95 (92.2) |
37 (90.2) |
0.956 |
|
Yes |
8 (7.8) |
4 (9.8) |
|
Postmortem diagnosis of NBTE (%)
|
No |
74 (71.8) |
21 (51.2) |
0.031 |
|
Yes |
29 (28.2) |
20 (48.8) |
|
Position of vegetation (n = 132) (%)
|
Aortic |
29 (31.2) |
19 (48.7) |
0.008 |
|
Left atrium |
1 (1.1) |
0 (0.0) |
|
|
Mitral |
42 (45.2) |
20 (51.3) |
|
|
Multiple |
21 (22.6) |
0 (0.0) |
|
Valve insufficiency (n = 89) (%)
|
No |
23 (35.4) |
5 (20.8) |
0.292 |
|
yes |
42 (64.6) |
19 (79.2) |
|
Valve stenosis (n = 90) (%)
|
No |
57 (86.4) |
24 (100.0) |
0.131 |
|
Yes |
9 (13.6) |
0 (0.0) |
|
Underwent intervention (%)
|
No |
84 (81.6) |
39 (95.1) |
0.069 |
|
Yes |
19 (18.4) |
2 (4.9) |
|
Type of surgery (%)
|
Excision of vegetation |
4 (3.9) |
1 (2.4) |
0.096 |
|
None |
84 (81.6) |
39 (95.1) |
|
|
Replacement |
15 (14.6) |
1 (2.4) |
|
Presenting symptoms (n = 139) (%)
|
Cardiological |
4 (4.2) |
2 (5.6) |
0.467 |
|
Neurological |
68 (70.8) |
28 (77.8) |
|
|
Others |
4 (4.2) |
3 (8.3) |
|
|
Respiratory |
11 (11.5) |
2 (5.6) |
|
|
Vascular |
9 (9.4) |
1 (2.8) |
|
Death (144) (%)
|
No |
37 (36.3) |
8 (20.0) |
0.094 |
|
Yes |
65 (63.7) |
32 (80.0) |
|
Time to death (days) (median (IQR))
|
|
19.60 (1.05, 56.00) |
10.99 (3.50, 35.28) |
0.64 |