Table 1.
List of the most relevant clinicopathological characteristics of patients treated in first-line therapy (Pembro cohort, PC) or in second/further lines of treatment (Nivo cohort, NC).
| Characteristics | PC | NC |
|---|---|---|
| Median age at start of therapy (Range) | 70.1 (50.5–88.8) | 70.1 (44.2–87.6) |
| Gender | N (%) | N (%) |
| Male | 43 (76.8) | 91 (72.2) |
| Female | 13 (23.2) | 35 (27.8) |
| Smoking habit | N (%) | N (%) |
| Never | 2 (3.6) | 10 (7.9) |
| Former | 31 (55.4) | 70 (55.6) |
| Current | 21 (37.5) | 44 (34.9) |
| Missing | 2 (3.6) | 2 (1.6) |
| ECOG-PS | N (%) | N (%) |
| 0 | 19 (33.9) | 29 (23.0) |
| 1 | 27 (48.2) | 82 (65.1) |
| 2 | 10 (17.9) | 14 (11.1) |
| 3 | 0 (0.0) | 1 (0.8) |
| Histotype | N (%) | N (%) |
| Adenocarcinoma | 29 (51.8) | 90 (71.4) |
| Squamous cell carcinoma | 14 (25.0) | 30 (23.8) |
| Other | 13 (23.2) | 6 (4.8) |
| Stage | N (%) | N (%) |
| IIIB | 0 (0.0) | 6 (4.8) |
| IV | 56 (100.0) | 120 (95.2) |
| Therapy line | N (%) | N (%) |
| 1st | 56 (100) | 0 (0.0) |
| 2nd | 0 (0.0) | 76 (60.3) |
| 3rd | 0 (0.0) | 29 (23.0) |
| Other | 0 (0.0) | 21 (16.7) |
| Cycles of therapy received | N (%) | N (%) |
| 1–8 | 27 (48.2) | 69 (54.8) |
| 9–123 | 29 (51.8) | 56 (44.4) |
| Missing | 0 (0.0) | 1 (0.8) |
| Total | 56 (100.0) | 126 (100.0) |