Table 2.

Cancer-associated fibroblasts recruit pro-tumor immune cells while inhibiting recruitment of anti-tumor immune cells.

CAF Subtype	Factor	Effect	Cancer Type	Reference
eCAF	Macrophages	M2 polarization	GC	[103]
Not determined	Monocytes	Differentiation into macrophages and recruitment to tumors	CRC and breast	[72,73]
Not determined	Mast cells	Mast cell degranulation	GC	[104]
Not determined	Natural killer cells	Reduction in NK cytotoxicity	PDAC	[105]
Not determined	Neutrophils	Neutrophil chemotaxis	HCC	[106]
apCAF	Tregs	T-cell differentiation into Tregs	PDAC	[107]
High-CAF	Helper T cells	Reduced helper T population	HNSCC	[108]
apCAFs	Cytotoxic T cells	Suppression of cytotoxic T cells	PDAC	[12]