Table 1.
Characteristics and ventilatory support of the subjects included in the study.
| Group 1 (n = 48) |
Group 2 (n = 41) |
p Value | |
|---|---|---|---|
| Sociodemographic and clinical data | |||
| Age (years), median (range) | 66 (25–90) | 63 (40–76) | 0.403 |
| Sex (male), n (%) | 31 (64) | 33 (80) | 0.106 |
| BMI (Kg/m2), median (range) | 30 (15–41) | 32.9 (25–33) | 0.499 |
| BMI > 30 (Kg/m2), n (%) | 18 (38) | 18 (44) | 0.665 |
| Smoking habit, n (%) | 0.041 | ||
| Smoker | 4 (8) | 11 (27) | 0.025 |
| Former smoker | 21 (44) | 11 (27) | 0.123 |
| Non-smoker | 21 (44) | 16 (39) | 0.673 |
| Survival, n (%) | 40 (83) | 30 (73) | 0.303 |
| Respiratory comorbidities, n (%) | |||
| Asthma | 2 (4) | 0 (0) | 0.497 |
| Obstructive sleep apneas | 5 (10) | 0 (0) | 0.059 |
| Chronic obstructive pulmonary disease | 5 (10) | 0 (0) | 0.059 |
| Bronchiectasis | 0 | 1 (2) | 0.461 |
| Pulmonary arterial hypertension | 2 (4) | 0 (0) | 0.497 |
| Pulmonary fibrosis | 1 (2) | 0 (0) | 1.000 |
| Other interstitial diseases | 2 (4) | 0 (0) | 0.497 |
| Lung transplant | 2 (4) | 0 (0) | 0.497 |
| Non-respiratory comorbidities, n (%) | |||
| Arterial hypertension | 24 (50) | 20 (49) | 1.000 |
| Obesity | 18 (38) | 18 (44) | 0.665 |
| Diabetes | 12 (25) | 7 (17) | 0.441 |
| Chronic renal insufficiency | 6 (12) | 3 (7) | 0.498 |
| Immunosuppression | 3 (6) | 2 (5) | 1.000 |
| Ischemic heart disease | 7 (15) | 1 (2) | 0.065 |
| Heart failure | 1 (2) | 0 (0) | 1.000 |
| Atrial fibrillation | 3 (6) | 0 (0) | 0.246 |
| Other cardiac diseases | 4 (8) | 2 (5) | 0.683 |
| Solid cancer | 13 (27) | 2 (5) | 0.009 |
| Cured | 6 (46) | 2 (100) | 0.467 |
| Leukemia | 3 (6) | 0 (0) | 0.246 |
| Psychiatric disease | 5 (10) | 3 (7) | 0.721 |
| Gastroesophageal reflux | 0 (0) | 1 (2) | 1.000 |
| Ventilatory support, n (%) | (n = 47) | (n = 40) | |
| Yes | 21 (45) | 40 (100) | <0.0001 |
| Type of support, n (%) | |||
| High-flow nasal cannula (HFNC) | 18 (86) | 26 (65) | 0.133 |
| Non-invasive mechanical ventilation (NIMV) | 3 (14) | 2 (5) | 0.329 |
| Invasive mechanical ventilation (IMV) | 13 (62) | 37 (93) | 0.005 |
| Extracorporeal membrane oxygenation | 1 (5) | 4 (10) | 0.651 |
| Oxygen therapy 100% | 2 (10) | 3 (8) | 1.000 |
A single patient may present more than one comorbidity or ventilatory support. Percentages in each line are calculated from the total population, except for patients with a neoplasia considered cured and type of ventilatory support, where percentages are calculated from the population with solid cancer and the population with support requirements, respectively. Some variables have missing values: Group 1 (2 for smoking habit, 1 for ventilatory support); Group 2 (3 for smoking habit, 1 for ventilator support).