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Receiver operating characteristic analysis of 3D VCA (AUC = 0.98) and AROA (AUC = 0.94). Graphical plotting of sensitivity and specificity using different methods to distinguish moderate and severe FMR classified by EROA 2D PISA (cut-off ≥ 0.2 cm2). Abbreviations: AUC = area under the curve; 3D = three-dimensional; VCA = vena contracta area; AROA = anatomic regurgitation area.
