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. 2023 Mar 8;12(6):838. doi: 10.3390/cells12060838

Table 1.

Morphological alterations in the kidneys, depending on the time of ischemia.

15 Min of Ischemia 25 Min of Ischemia and 120 Min after Blood Reflow 60 Min of Ischemia and 120 Min after Blood Reflow
Insignificant black leak
Minimal invertible injury to tubular cells
No evolution changes to necrosis
Modest back leak
Expansion of cell injury to necrosis in single cells, but convoluted proximal tubules are not involved
Severe black leak
Necrosis in convoluted and straight proximal tubular cells, irreparable cell injury, and necrotic cells and sporadic areas of the tubular basement membrane are stripped of epithelium