ALS	amyotrophic lateral sclerosis
CNS	central nervous system
fALS	familial amyotrophic lateral sclerosis
sALS	sporadic amyotrophic lateral sclerosis
FDA	Food and Drug Administration
iPSCs	induced pluripotent stem cells
ESCs	embryonic stem cells
MNs	motor neurons
hiPSCs	human induced pluripotent stem cells
iPSCs-MNs	induced pluripotent stem cells derived motor neurons
ESCs-MNs	embryonic stem cells derived motor neurons
NPCs	neural progenitor cells
iPSCs-NPCs	induced pluripotent stem cells derived neural progenitor cells
NSCs	neural stem cells
iPSCs-NSCs	induced pluripotent stem cells derived neural stem cells
NMJ	neuromuscular junction
SOD1	superoxide dismutase 1
C9orf72	chromosome nine open reading frame 72
TARDBP	TAR DNA binding protein
FUS	fused in sarcoma
NfH	neurofilament heavy chain
NfL	neurofilament light chain
CSF	cerebrospinal fluid
HD-MEAs	high density microelectrode-arrays
DPR	dipeptide repeat
TDP-43	TAR DNA binding protein 43
RNAP II	RNA polymerase II
EAAT2	excitatory amino acid transporter 2
SG	stress granule
G3BP1	GTPase activating protein (SH3 domain) binding protein 1
Il-1α	interleukin 1α
TNF	tumor necrosis factor
C1q	complement component 1, subcomponent q
ROPI	ropinirole
HDAC	histone deacetylase
FTD	frontotemporal dementia
STAT3	signal transducer and activator of transcription 3
TGF-β	transforming growth factor-β