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. 2023 Mar 8;12(6):836. doi: 10.3390/cells12060836

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Genes regulated by KDM6A are implicated in notch signaling. (A,B) Analysis of the genes involved in cell surface receptor signaling for IH-MULTI (A) and normal-immortal clusters (B). Interaction data obtained from String was visualized using Cytoscape. (C–E) Snapshot images showing KDM6A signal in BdEC, SV-HUC-1, and T24 cell lines at HES1 (C), TLE3 (D), and JAG2 (E) loci. (F) Manually created cartoon showing the genes involved in Notch signaling and associated with KDM6A peaks (A,B). Genes marked with KDM6A signal are highlighted in green.