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. 2023 Mar 8;13(6):1031. doi: 10.3390/diagnostics13061031

Table 1.

Causes of noncirrhotic portal hypertension.

PREHEPATIC INTRAHEPATIC POSTSINUSOIDAL
  • -

    Portal vein thrombosis

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    Splenic vein thrombosis

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    Splenomegaly due to other causes (e.g., Gaucher’s disease, lymphoma)

 Presinusoidal
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    Schistosomiasis

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    Idiopathic portal hypertension

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    Primary biliary cholangitis

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    Sarcoidosis

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    Congenital hepatic fibrosis

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    Primary sclerosing cholangitis

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    Hepatic arteriopetal fistula

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    Adult polycystic liver disease

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    Arteriovenous fistulas

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    Autoimmune cholangiopathy

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    Peliosis hepatis

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    Neoplastic occlusion of the intrahepatic portal vein
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    Inferior vena cava obstruction (e.g., Budd–Chiari syndrome)
Sinusoidal
  • -

    Arsenic poisoning

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    Vinyl chloride toxicity

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    Drugs (e.g., amiodarone, methotrexate)

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    Alcoholic liver disease

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    Nonalcoholic fatty liver disease

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    Acute fatty liver of pregnancy

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    Acute hepatic injury

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    Gaucher’s disease

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    Viral hepatitis

  • -

    Schistosomiasis

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    Amyloidosis

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    Mastocytosis

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    Agnogenic myeloid metaplasia

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    Chronic Q fever

Postsinusoidal
  • -

    Budd–Chiari syndrome

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    Sinusoidal obstruction syndrome (veno-occlusive disease)

  • -

    Alcoholic liver disease

  • -

    Chronic radiation injury

  • -

    Angiosarcoma

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    Hemangioendothelioma

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    Sarcoidosis