Table A4.
Candidate genes encoding key enzymes in antipsychotic metabolism.
| Gene (OMIM Number *) |
Chromosome Location ** |
Genomic Coordinate ** | Protein *** |
|---|---|---|---|
| CYP1A2 (124060) | 15q24.1 | chr15:74,748,845–74,756,607(GRCh38/hg38) | Cytochrome P450 Family 1 Subfamily A Member 2 |
| CYP2C9 (601130) | 10q23.33 | chr10:94,938,658–94,990,091(GRCh38/hg38) | Cytochrome P450 Family 2 Subfamily C Member 9 |
| CYP2C19 (124020) | 10q23.33 | chr10:94,762,681–94,855,547(GRCh38/hg38) | Cytochrome P450 Family 2 Subfamily C Member 19 |
| CYP2D6 (124030) | 22q13.2 | chr22:42,126,499–42,130,865(GRCh38/hg38) | Cytochrome P450 Family 2 Subfamily D Member 6 |
| CYP3A4 (124010) | 7q22.1 | chr7:99,756,960–99,784,248(GRCh38/hg38) | Cytochrome P450 Family 3 Subfamily A Member 4 |