Table A6.
Transporter proteins and their encoding genes.
| Gene (OMIM * Number) |
Chromosome Location ** |
Genomic Coordinate ** | Protein *** |
|---|---|---|---|
| ABCB1 (171050) | 7q21.12 | chr7:87,503,017–87,713,323(GRCh38/hg38) | Multidrug Resistance Protein 1 (MDR1) P-Glycoprotein 1 (P-gp) |
| ABCB2 (170260) | 6p21.32 | chr6:32,845,209–32,853,816(GRCh38/hg38) | Transporter 1 (TAP1) |
| ABCB3 (170261) | 6p21.32 | chr6:32,821,831–32,838,770(GRCh38/hg38) | Transporter 2 (TAP2) |
| ABCB4 (171060) | 7q21.12 | chr7:87,398,988–87,480,435(GRCh38/hg38) | Multidrug Resistance Protein 3 (MDR2) P-Glycoprotein 3 |
| ABCB11 (603201) | 2q31.1 | chr2:168,915,468–169,031,396(GRCh38/hg38) | Bile Salt Export Pump (BSEP) |
| ABCC1 (158343) | 16p13.11 | chr16:15,949,138–16,143,257(GRCh38/hg38) | Protein associated with multidrug resistance (MRP1) |
| ABCC2 (601107) | 10q24.2 | chr10:99,782,602–99,853,741(GRCh38/hg38) | Multidrug Resistance-Associated Protein 2 (MRP2) |
| ABCC3 (604323) | 17q21.33 | chr17:50,634,777–50,692,253(GRCh38/hg38) | Multidrug Resistance-Associated Protein 3 (MRP3) |
| ABCC4 (605250) | 13q32.1 | chr13:95,019,835–95,301,475(GRCh38/hg38) | Multidrug Resistance-Associated Protein 4 (MRP4) |
| ABCC5 (605251) | 3q27.1 | chr3:183,919,934–184,018,010(GRCh38/hg38) | Multidrug Resistance-Associated Protein 5 (MRP5) |
| ABCC6 (603234) | 16p13.11 | chr16:16,149,565–16,223,617(GRCh38/hg38) | Multidrug Resistance-Associated Protein 6 (MRP6) |
| ABCC1 (612509) | 6p21.1 | chr6:43,427,366–43,451,994(GRCh38/hg38) | Multidrug Resistance-Associated Protein 7 (MRP7) |
| ABCC11 (607040) | 16q12.1 | chr16:48,164,842–48,249,973(GRCh38/hg38) | Multidrug Resistance-Associated Protein 8 (MRP8) |
| ABCC12 (607041) | 16q12.1 | chr16:48,080,882–48,156,018(GRCh38/hg38) | Multidrug Resistance-Associated Protein 9 (MRP9) |
| ABCG2 (603756) | 4q22.1 | chr4:88,090,150–88,231,628(GRCh38/hg38) | Breast cancer resistance protein (BCRP) |
Note: * from the open database OMIM—Online Mendelian Inheritance in Man [78], ** from the open database GeneCards: The Human Gene Database [86], *** from the open database The Human Protein Atlas [81], ABCB1—ATP Binding Cassette Subfamily B Member 1, ABCG2—ATP-Binding Cassette Sub-family G member 2, and ABCC1—ATP Binding Cassette Subfamily C Member 1.