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. 2023 Mar 18;9(3):239. doi: 10.3390/gels9030239

Figure 5.

Figure 5

Hybrid DNA hydrogel prepared through HCR strategy for cancer therapy. (A) Schematic of the preparation and drug release of hybrid DNA nanogel. Reproduced with permission. Copyright 2021 [52], Nature Portfolio. (B) The principle of hybrid DNA nanogel based on C-HCR-synthesized networks. Reproduced with permission. Copyright 2021 [51], Wiley-VCH Verlag GmbH. (C) The schematic of pH-responsive hybrid DNA hydrogel for the DOX release. (D) Cytotoxicity assay of the pH-responsive hydrogel loaded with DOX into MCF-10A cells and MDA-MB-231 malignant breast cancer cells. *** p < 0.001. Reproduced with permission. Copyright 2017 [53], Royal Society Chemistry.